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  2. Plastids are usually involved in photosynthesis, but the secondary loss of this function is a widespread phenomenon in various lineages of algae and plants. In addition to the loss of genes associated with pho...

    Authors: Kacper Maciszewski, Gabriela Wilga, Tomasz Jagielski, Zofia Bakuła, Jan Gawor, Robert Gromadka and Anna Karnkowska
    Citation: BMC Biology 2024 22:294
    Content type: Research article Published on:

  3. The mutualistic beneficial relationship between legume plants and rhizobia enables the growth of plants in nitrogen-limiting conditions. Rhizobia infect legumes through root hairs and trigger nodule organogene...

    Authors: Jingjing Cao, Yu Zhou, Tao Tian, Jie Ji, Yan Deng, Yuhao Guan, Yongmei Qi, Longxiang Wang, Longlong Wang, Yibo Huang, Qiuling Fan and Deqiang Duanmu
    Citation: BMC Biology 2024 22:293
    Content type: Research article Published on:

  4. The intracellular bacterium Listeria monocytogenes is an attractive vector for cancer immunotherapy as it can effectively deliver tumor antigens to antigen-presenting cells, leading to a robust antitumor response...

    Authors: Jing Sun, Jing Wang, Xin Jiang, Jing Xia, Yue Han, Mianmian Chen, Jiali Xu, Simin Deng, Changyong Cheng and Houhui Song
    Citation: BMC Biology 2024 22:291
    Content type: Research Published on:

  5. The harmonious operation of many insect societies depends upon colony-wide dissemination of a non-volatile pheromone produced by a single queen, which informs workers of her presence. This represents a major c...

    Authors: Thomas O. Richardson, Tomas Kay, Laurent Keller and Nathalie Stroeymeyt
    Citation: BMC Biology 2024 22:288
    Content type: Research article Published on:

  6. Gaining a comprehensive understanding of the genetic mechanisms underlying insecticide resistance in malaria vectors is crucial for optimising the effectiveness of insecticide-based vector control methods and ...

    Authors: Nelly M. T. Tatchou-Nebangwa, Leon M. J. Mugenzi, Abdullahi Muhammad, Derrick N. Nebangwa, Mersimine F. M. Kouamo, Carlos S. Djoko Tagne, Theofelix A. Tekoh, Magellan Tchouakui, Stephen M. Ghogomu, Sulaiman S. Ibrahim and Charles S. Wondji
    Citation: BMC Biology 2024 22:286
    Content type: Research Published on:

  8. Microgenderome or arguably more accurately microsexome refers to studies on sexual dimorphism of human microbiomes aimed at investigating bidirectional interactions between human microbiomes, sex hormones, and...

    Authors: Zhanshan Sam Ma
    Citation: BMC Biology 2024 22:284
    Content type: Research article Published on:

    The Methodology article to this article has been published in BMC Biology 2024 22:283

  9. Differentiating the microbiome changes associated with diseases is challenging but critically important. Majority of existing efforts have been focused on a community level, but the discerning power of communi...

    Authors: Zhanshan Sam Ma
    Citation: BMC Biology 2024 22:283
    Content type: Methodology article Published on:

    The Research article to this article has been published in BMC Biology 2024 22:284

  10. The expansion of CAG/CTG repeats in functionally unrelated genes is a causative factor in many inherited neurodegenerative disorders, including Huntington’s disease (HD), spinocerebellar ataxias (SCAs), and my...

    Authors: Pawel Sledzinski, Mateusz Nowaczyk, Marianna Iga Smielowska and Marta Olejniczak
    Citation: BMC Biology 2024 22:282
    Content type: Research article Published on:

  11. In trypanosomatids, a group of unicellular eukaryotes that includes numerous important human parasites, cis-splicing has been previously reported for only two genes: a poly(A) polymerase and an RNA helicase. Conv...

    Authors: Alexei Yu. Kostygov, Karolína Skýpalová, Natalia Kraeva, Elora Kalita, Cameron McLeod, Vyacheslav Yurchenko, Mark C. Field, Julius Lukeš and Anzhelika Butenko
    Citation: BMC Biology 2024 22:281
    Content type: Research Published on:

  12. Inflammatory bowel disease (IBD), a persistent gastrointestinal disease, is featured with impaired gut immunity. Previous studies have demonstrated that tuft cells can regulate the intestinal type 2 immune res...

    Authors: Yuxuan Yang, Wenqing Li, Kaineng Sun, Siyu Sun, Yong Zhang, Lin Chen, Yangyue Ni, Min Hou, Zhipeng Xu, Lu Chen and Minjun Ji
    Citation: BMC Biology 2024 22:280
    Content type: Research article Published on:

  15. The tree shrew (Tupaia belangeri) is a promising emerging model organism in biomedical studies, notably due to their evolutionary proximity to primates. To enhance our understanding of how DNA methylation is impl...

    Authors: Dongmin R. Son, Yifan Kong, Yulian Tan, Ting Hu, Lei Shi and Soojin V. Yi
    Citation: BMC Biology 2024 22:277
    Content type: Research Published on:

  16. The β-adrenergic augmentation of cardiac contraction, by increasing the conductivity of L-type voltage-gated CaV1.2 channels, is of great physiological and pathophysiological importance. Stimulation of β-adrenerg...

    Authors: Shimrit Oz, Tal Keren-Raifman, Tom Sharon, Suraj Subramaniam, Tamara Pallien, Moshe Katz, Vladimir Tsemakhovich, Anastasiia Sholokh, Baraa Watad, Debi Ranjan Tripathy, Giorgia Sasson, Orna Chomsky-Hecht, Leonid Vysochek, Maike Schulz-Christian, Claudia Fecher-Trost, Kerstin Zühlke…
    Citation: BMC Biology 2024 22:276
    Content type: Research article Published on:

  18. Early in the coronavirus disease 2019 (COVID-19) pandemic, Sunda pangolins (Manis javanica) involved in the illegal wildlife trade in mainland China were identified as hosts of severe acute respiratory syndrome-r...

    Authors: Brian M. Worthington, Portia Y.-H. Wong, Kishoree K. Kumaree, Tracey-Leigh Prigge, Kar Hon Ng, Yunshi Liao, Paolo Martelli, Sarah Churgin, Foo K. Lee, Chris Perkins, Michael Bradley, Mac P. Pierce, Marcus H.-H. Shum, Elliott F. Miot, William Y.-M. Cheung, Shelby E. McIlroy…
    Citation: BMC Biology 2024 22:274
    Content type: Research article Published on:

  19. Accurate and comprehensive genomic annotation, including the full list of protein-coding genes, is vital for understanding the molecular mechanisms of human biology. We have previously shown that the genome co...

    Authors: Lu Tang, Dongyang Xu, Lingcong Luo, Weiyan Ma, Xiaojie He, Yong Diao, Rongqin Ke and Philipp Kapranov
    Citation: BMC Biology 2024 22:273
    Content type: Research Published on:

  20. Understanding how ectotherms manage energy in response to temperature is crucial for predicting their responses to climate change. However, the complex interplay between developmental and adult thermal conditi...

    Authors: Diana Knoblochová, Malleswara Dharanikota, Martina Gáliková and Peter Klepsatel
    Citation: BMC Biology 2024 22:272
    Content type: Research Published on:

  21. It is generally accepted that nuclear genes in eukaryotes are located independently on chromosomes and expressed in a monocistronic manner. However, accumulating evidence suggests a more complex landscape of g...

    Authors: Lining Wang, Peiqi Shi, Zhaohua Ping, Qinghua Huang, Liqun Jiang, Nianfang Ma, Qingfu Wang, Jiang Xu, Yajie Zou and Zhihai Huang
    Citation: BMC Biology 2024 22:271
    Content type: Research article Published on:

  22. Extinct organisms provide vital information about the time of origination and biogeography of extant groups. The development of phylogenetic methods to study evolutionary processes through time has revolutioni...

    Authors: Raquel López-Antoñanzas, Tiago R. Simões, Fabien L. Condamine, Moritz Dirnberger and Pablo Peláez-Campomanes
    Citation: BMC Biology 2024 22:270
    Content type: Research article Published on:

  23. Wolbachia incompatible insect technique (IIT) programs have been shown in field trials to be highly effective in suppressing populations of mosquitoes that carry diseases such as dengue, chikungunya, and Zika. Ho...

    Authors: Preston LJ Lim, Alex R Cook, Somya Bansal, Jo Yi Chow and Jue Tao Lim
    Citation: BMC Biology 2024 22:269
    Content type: Research Published on:

  24. Dietary restriction (DR) has multiple beneficial effects on health and longevity and can also improve the efficacy of certain therapies. Diets used to instigate DR are diverse and the corresponding response is...

    Authors: Helene Michenthaler, Kalina Duszka, Isabel Reinisch, Markus Galhuber, Elisabeth Moyschewitz, Sarah Stryeck, Tobias Madl, Andreas Prokesch and Jelena Krstic
    Citation: BMC Biology 2024 22:268
    Content type: Research article Published on:

  25. Ancient Chang’an in the Tang Dynasty (618–907 AD) was one of the world’s largest and most populated cities and acted as the eastern end of the world-famous Silk Road. However, little is known about the genetic...

    Authors: Minglei Lv, Hao Ma, Rui Wang, Hui Li, Xiangyu Zhang, Wenbo Zhang, Yuding Zeng, Ziwei Qin, Hongbo Zhai, Yiqiang Lou, Yukai Lin, Le Tao, Haifeng He, Xiaomin Yang, Kongyang Zhu, Yawei Zhou…
    Citation: BMC Biology 2024 22:267
    Content type: Research Published on:

  26. Insects detect odours using odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs) in the antennae. Ecologically important odours are often detected by selective and abundant OSNs; hence, ORs wi...

    Authors: Jothi Kumar Yuvaraj, Dineshkumar Kandasamy, Rebecca E. Roberts, Bill S. Hansson, Jonathan Gershenzon and Martin N. Andersson
    Citation: BMC Biology 2024 22:266
    Content type: Research article Published on:

  28. For decades, KRAS has always been a huge challenge to the field of drug discovery for its significance in cancer progression as well as its difficulties in being targeted as an “undruggable” protein. KRAS regu...

    Authors: Sanan Wu, Xiaoyang Gao, Di Wu, Lu Liu, Han Yao, Xiangjun Meng, Xianglei Zhang and Fang Bai
    Citation: BMC Biology 2024 22:264
    Content type: Research Published on:

  29. Tissue engineering techniques offer new strategies to understand complex processes in a controlled and reproducible system. In this study, we generated bilayered human tissue substitutes consisting of a cellul...

    Authors: Paula Ávila-Fernández, Miguel Etayo-Escanilla, David Sánchez-Porras, Ricardo Fernández-Valadés, Fernando Campos, Ingrid Garzón, Víctor Carriel, Miguel Alaminos, Óscar Darío García-García and Jesús Chato-Astrain
    Citation: BMC Biology 2024 22:263
    Content type: Research article Published on:

  30. Liver organoid serves as an alternative model for liver pathophysiology in carbohydrate or lipid metabolism and xenobiotic metabolism transformation. Biomechanical cues including spaceflight mission can affect...

    Authors: Shaoyu Zhong, Lu Zheng, Yi Wu, Shujin Sun, Qing Luo, Guanbin Song, Dongyuan Lü and Mian Long
    Citation: BMC Biology 2024 22:262
    Content type: Research Published on:

  31. Invasive management strategies range from preventing new invasive species incursions to eliminating established populations, with all requiring effective monitoring to guide action. The use of DNA sampled from...

    Authors: Antoinette J. Piaggio, Luke Gierus, Daniel R. Taylor, Nick D. Holmes, David J. Will, Neil J. Gemmell and Paul Q. Thomas
    Citation: BMC Biology 2024 22:261
    Content type: Methodology Published on:

  34. Tryptophan is an essential amino acid involved in critical cellular processes in vertebrates, serving as a precursor for serotonin and kynurenine, which are key neuromodulators to influence neural and immune f...

    Authors: Kui Wang, Tian-lun Chen, Xin-xin Zhang, Jian-bin Cao, Pengcheng Wang, Mingcang Wang, Jiu-lin Du, Yu Mu and Rongkun Tao
    Citation: BMC Biology 2024 22:258
    Content type: Research article Published on:

  35. Light is a key environmental regulator of physiology and behaviour. Mistimed or insufficient light disrupts circadian rhythms and is associated with impaired health and well-being across mammals. Appropriate l...

    Authors: Richard J. McDowell, Altug Didikoglu, Tom Woelders, Mazie J. Gatt, Finn Moffatt, Saba Notash, Roelof A. Hut, Timothy M. Brown and Robert J. Lucas
    Citation: BMC Biology 2024 22:257
    Content type: Research article Published on:

  36. The interactions between bacterial pathogens and host cells are characterized by a multitude of complexities, leading to a wide range of heterogeneous outcomes. Despite extensive research, we still have a limi...

    Authors: Narendra K. Dewangan, Sayed Golam Mohiuddin, Shayne Sensenbach, Prashant Karki and Mehmet A. Orman
    Citation: BMC Biology 2024 22:256
    Content type: Research article Published on:

  37. Evolutionary adaptation drives organismal adjustments to environmental pressures, exemplified in the diverse morphological and ecological adaptations seen in Decapoda crustaceans, particularly brachyuran crabs...

    Authors: Yin Zhang, Ye Yuan, Mengqian Zhang, Xiaoyan Yu, Bixun Qiu, Fangchun Wu, Douglas R. Tocher, Jiajia Zhang, Shaopan Ye, Wenxiao Cui, Jonathan Y. S. Leung, Mhd Ikhwanuddin, Waqas Waqas, Tariq Dildar and Hongyu Ma
    Citation: BMC Biology 2024 22:255
    Content type: Research Published on:

  38. The 3′ untranslated region (3′UTR) plays a crucial role in determining mRNA stability, localisation, translation and degradation. Cap analysis of gene expression (CAGE), a method for the detection of capped 5′...

    Authors: Nejc Haberman, Holly Digby, Rupert Faraway, Rebecca Cheung, Anob M. Chakrabarti, Andrew M. Jobbins, Callum Parr, Kayoko Yasuzawa, Takeya Kasukawa, Chi Wai Yip, Masaki Kato, Hazuki Takahashi, Piero Carninci, Santiago Vernia, Jernej Ule, Christopher R. Sibley…
    Citation: BMC Biology 2024 22:254
    Content type: Research Published on:

  39. NorR, as a single-target regulator, has been demonstrated to be involved in NO detoxification in bacteria under anaerobic conditions. Here, the norR gene was identified and deleted in the genome of Vibrio alginol...

    Authors: Tongxian Chen, Xiaoling Zhou, Ruonan Feng, Shuhao Shi, Xiyu Chen, Bingqi Wei, Zhong Hu and Tao Peng
    Citation: BMC Biology 2024 22:253
    Content type: Research article Published on:

    The Author Correction to this article has been published in BMC Biology 2024 22:285

  40. Understanding how genes function to heal wounds and restore lost tissue is essential for studying regeneration. Whole-mount in situ hybridization (WISH) is a powerful and widely used technique to visualize the...

    Authors: Carlos Guerrero-Hernández, Viraj Doddihal, Frederick G. Mann Jr. and Alejandro Sánchez Alvarado
    Citation: BMC Biology 2024 22:252
    Content type: Methodology article Published on:

  42. Climate change is driving increased extreme weather events that can impact ecology by moderating host–pathogen interactions. To date, few studies have explored how cold snaps affect disease prevalence and prol...

    Authors: Niamh McCartan, Jeremy Piggott, Sadie DiCarlo and Pepijn Luijckx
    Citation: BMC Biology 2024 22:250
    Content type: Research article Published on:

  43. The Leishmania genome harbors formerly active short interspersed degenerated retroposons (SIDERs) representing the largest family of repetitive elements among trypanosomatids. Their substantial expansion in Leish...

    Authors: Gabriel Reis Ferreira, Jean-Guillaume Emond-Rheault, Lysangela Alves, Philippe Leprohon, Martin A. Smith and Barbara Papadopoulou
    Citation: BMC Biology 2024 22:249
    Content type: Research Published on:

  44. Accurate prediction of compound-protein interaction (CPI) plays a crucial role in drug discovery. Existing data-driven methods aim to learn from the chemical structures of compounds and proteins yet ignore the...

    Authors: Wen Tao, Xuan Lin, Yuansheng Liu, Li Zeng, Tengfei Ma, Ning Cheng, Jing Jiang, Xiangxiang Zeng and Sisi Yuan
    Citation: BMC Biology 2024 22:248
    Content type: Research Published on:

  45. Mitochondria-endoplasmic reticulum membrane contact (MERC) is an important mode of intercellular organelle communication and plays a crucial role in adipose tissue metabolism. Functionality of Hoxa5 is an impo...

    Authors: Qi Chen, Zeyu Ren, Liping Dang, Zunhai Liu, Simeng Wang, Xinhao Chen, Guiping Qiu and Chao Sun
    Citation: BMC Biology 2024 22:247
    Content type: Research article Published on:

  46. The role of histone methyltransferase SETDB1 in renal ischemia–reperfusion (I/R) injury has not been explored yet. This study aims to investigate the potential mechanism of SETDB1 in regulating renal I/R injur...

    Authors: Kang Xia, Yumin Hui, Long Zhang, Qiangmin Qiu, Jiacheng Zhong, Hui Chen, Xiuheng Liu, Lei Wang and Zhiyuan Chen
    Citation: BMC Biology 2024 22:246
    Content type: Research article Published on:

  47. Thymosin beta 4 (Tβ4) is a monomeric actin-binding protein that plays many roles in biological activities. However, some studies on the role of Tβ4 in central axon regeneration have yielded contradictory resul...

    Authors: Zheng Song, Along Han and Bing Hu
    Citation: BMC Biology 2024 22:244
    Content type: Research article Published on:

  48. Single-domain von Willebrand factor type C (SVWC) constitute a protein family predominantly identified in arthropods, characterized by a SVWC domain and involved in diverse physiological processes such as host...

    Authors: Ting Tang, Siyu Sun, Ruirui Wang, Mengnan Li, Yongpeng Wang, Feifei Li, Yun Wang and Fengsong Liu
    Citation: BMC Biology 2024 22:242
    Content type: Research article Published on:

  49. The family Lauraceae is subdivided into six main lineages: Caryodaphnopsideae, Cassytheae, Cryptocaryeae, Hypodaphnideae, Laureae, and Neocinnamomeae. However, phylogenetic relationships among these lineages h...

    Authors: Yu Song, Qun-Fei Yu, Di Zhang, Li-Gang Chen, Yun-Hong Tan, Wen Zhu, Hua-Long Su, Xin Yao, Chao Liu and Richard T. Corlett
    Citation: BMC Biology 2024 22:241
    Content type: Research article Published on:

  50. The rumen microbiome plays an essential role in maintaining ruminants’ growth and performance even under extreme environmental conditions, however, which factors influence rumen microbiome stability when rumin...

    Authors: Wei Guo, Mi Zhou, Fuyong Li, André Luis Alves Neves, Tao Ma, Sisi Bi, Weiwei Wang, Ruijun Long and Le Luo Guan
    Citation: BMC Biology 2024 22:240
    Content type: Research article Published on:
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