Fig. 3
From: Transcriptomic signatures of oxytosis/ferroptosis are enriched in Alzheimer’s disease
Single-cell enrichment analysis. A Enrichment of the FerrDb, TrioSig, Ferroptosis, Apoptosis, Necroptosis, and Autophagy signatures in single-cell transcriptomic data (DE genes between control and disease) of 5xFAD male mice. CX, cortex. All DE genes together as well as separated by direction of expression (Down and Up) were analyzed. B Enrichment of the FerrDb, TrioSig, Ferroptosis, Apoptosis, Necroptosis, and Autophagy signatures in single-cell transcriptomic data (DE genes between control and AD) of several brain regions from human AD patients. PFC, prefrontal cortex; SFG, superior frontal gyrus; EC, caudal entorhinal cortex. All DE genes together as well as separated by direction of expression (Down and Up) were analyzed