Fig. 6
From: Transcriptome analysis reveals PTBP1 as a key regulator of circRNA biogenesis
PTBP1-related circRNAs are associated with cell proliferation in AML. A–C Gene set enrichment analysis (GSEA) shows the significant pathway enriched in differentially expressed genes in AML. Normalized enrichment score (NES) reflects the enrichment level of differentially expressed genes associated with specific pathway relative to all differentially expressed genes. D GO enrichment of differentially expressed genes in ceRNA network. The outer circle represents 15 GO terms enriched in MF, BP, and CC. The middle circle represents the number of differentially expressed genes enriched in the corresponding GO terms, with the color representing the significance of the enrichment. The inner circle represents the gene ratio. E Dot plot shows five KEGG pathways enriched with differentially expressed genes in ceRNA network. F CeRNA networks of six hub circRNAs associated with cell proliferation