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Fig. 6 | BMC Biology

Fig. 6

From: A single-cell transcriptomic atlas of all cell types in the brain of 5xFAD Alzheimer mice in response to dietary inulin supplementation

Fig. 6

Astrocyte subpopulations distributed in a region-specific manner. UMAP of astrocytes (A) and microglia (D) in the forebrain, interbrain, and brainstem of Ctrl_AD and Inulin_AD mice. Violin plot of marker gene expression level of astrocytes (B) and microglia (E). Cell proportion comparison of astrocyte (C) and microglia (F) subtypes among the three regions. Each dot represented one independently sequenced mouse. Two-way ANOVA with Tukey’s multiple comparisons test was used to determine statistical significance. Data were presented in mean ± SD. GO analysis of DEGs in astrocyte (G) and microglia (H) subpopulations. LPS, lipopolysaccharide

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BMC Biology

ISSN: 1741-7007

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