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Fig. 3 | BMC Biology

Fig. 3

From: Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation

Fig. 3

5hmC peaks associated with differential gene expression. A KEGG analysis of 5hmC marked genes that gain 5hmC in liver metastasis. B Volcano plot for gene expression changes after metastatic transition (data from [28]). Darker dots identify genes with at least one overlapping and significantly enriched 5hmC peak in hMeDIP-seq. C A core cadherin 2 (CDH2) and fibrinogen (FN1) network of associations for genes that have increased 5hmC and upregulated expression during metastasis

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BMC Biology

ISSN: 1741-7007

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