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Table 1 Comparison of bone marrow cell proportions between WT and ADO2 groups using the chi-square test

From: SUGAR-seq reveals the transcriptome and N-linked glycosylation landscape of mononuclear phagocytes at single-cell resolution in a mouse model of autosomal dominant osteopetrosis type 2

Cluster

WT count

ADO2 count

Chi-square

P-value

GMP

722

657

23.420

 < 0.001*

Pre_B

89

126

2.401

0.153

ProEryth

255

211

16.260

 < 0.001*

HSCs

91

118

0.610

0.435

MatureB

243

342

5.384

0.020*

PlasmaCells

14

68

28.799

 < 0.001*

TandNK

196

293

7.683

0.006*

Neutrophils

3233

3575

9.329

0.002*

Basophils

71

105

2.475

0.116

Eosinophils

7

6

0.305

0.581

Macrophages

40

34

1.841

0.175

Monocytes

837

1066

4.457

0.035*

cDCs

91

165

11.928

0.001*

pDCs

133

243

18.305

 < 0.001*

SUM

6022

7009

  
  1. The chi-square test of fourfold contingency tables was used to compare the cell proportions between the WT and ADO2 groups. SUM represents the total number of cells annotated in the bone marrow. The p-value represents the statistical significance of the differences observed (* P < 0.05)