Fig. 3

Overview of cell cluster analysis and distribution across ADO2 and WT groups. a Dot plot graph showing the normalized expression levels of marker genes in each of the 14 identified cell clusters. b UMAP clustering plots of 13,031 cells from the two groups, which provides an overview of the sample distribution between the ADO2 and WT groups. c UMAP plot visualizing the 14 distinct cell types across ADO2 and WT groups, uniquely colored and labeled. d Pie charts representing the frequency of cell clusters in the ADO2 and WT groups. Each cluster is colored and labeled, with the area of each sector reflecting its frequency in the respective groups. e Pseudocolor plot showing the proportion of neutrophils in bone marrow cells in the ADO2 and WT groups