Fig. 1

Single cell expression and chromatin accessibility patterns during human spermatogenesis. Dimension reduction (UMAP) plots of scRNA-seq (A) and scATAC-seq (B) dataset; cell state annotations are derived from marker gene expression in (A) [34]. The same data are projected onto a single plot, with the population of origin indicated in (C) and cell annotations shown in (D). In (C), scATAC-seq data are shown in grey and scRNA-seq data in black