Fig. 4

Evolutionary conservation of the major QTL region for VNN. A “Peaks and Valleys” graph showing the percentage of conservation of the European sea bass VNN resistance QTL region (Chromosome 3: 10,075168–10,097,914) with the homologous region in M. saxatilis (NCBI NW_023339873.1: 15,596,712–15,606,764), “peaks” indicate high similarity between the two species, while “valleys” indicate low similarity. B Multiple sequence alignment plot of the Amino acid sequences of the five interferon-induced genes in the VNN resistance QTL region of European sea bass, where letters correspond to the standard abbreviation of amino acid residues in the peptide sequences, while “-” represents a gap in the alignments. C IFI27L2-like gene tree reconstructed using Bayesian inference. GeneIDs are reported at the branch tips for consistency throughout the document, but the corresponding coding mRNA sequences were used for the analysis (D. labrax: LOC127358678—XM_051391955.1, LOC127358685—XM_051391968.1, LOC127358630—XM_051391880.1; S. aurata: LOC115566036—XM_030391784.1, LOC115597424—XM_030443305.1, LOC115565917—XM_030391575.1, and LOC115565919—XM_030391576.1; M. saxatilis: LOC118337083—XM_035673933.1, LOC118337072—XM_035673917.1, LOC118337084—XM_035673934.1, LOC118337082—XM_035673932.1). Numbers at nodes are posterior probability values