Fig. 2

Epigenomic and transcriptomic divergence between ecotypes. Heatmaps of (a, b) differentially expressed genes (DEGs), (c, d) differentially spliced genes (DSGs), (e, f) differentially expressed miRNAs (DEmiRs), and (g, h) differentially methylated cytosines (DMCs) in brain and liver tissues. Each column represents one sample, and each row represents one DEG/DSG/DEmiR/DMC. Columns and rows are both clustered using the “complete” clustering method based on Euclidean distances of samples or DEGs/DSGs/DEmiRs/DMCs. The color bar represents relative expression or methylation level, where darker red indicates higher expression or methylation level, while darker blue indicates lower expression or methylation level in that sample. The numbers of (a, b) DEGs, (c, d) DSGs, (e, f) DEmiRs, and (g, h) DMCs used for clustering are indicated in parentheses