Fig. 5
From: Switching of OAS1 splicing isoforms overcomes SNP-derived vulnerability to SARS-CoV-2 infection
Calu-3 cells with stable OAS1 p44a isoform expression exhibit mitigated SARS-CoV-2 infection. a RT-PCR results for the p42 and p44a isoforms of OAS1 mRNAs in parental and stably overexpressing the OAS1 p44a isoform Calu-3 cells. ACTB served as the loading control. b Box plots showing logarithm translated virus titers. Center line, median; box limits, upper and lower quartiles; whiskers, 1.5 × interquartile range; *p < 0.05 by two-sided Student’s t-test