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Fig. 5 | BMC Biology

Fig. 5

From: Transcriptomic profile of RNA pseudouridine modification as a biomarker for cellular senescence associated with survival outcomes in colorectal cancer

Fig. 5

Association of Psi Score and Cellular Senescence with prognostic outcomes and biological pathway activation in CRC. A The four-quadrant diagram of the Psi Score and CS Score. Psi-independent CS: Psi-independent cellular senescence. Psi-related CS: Psi-related cellular senescence. Psi-related non-CS: Psi-related non-cellular senescence. Psi-waived non-CS: Psi-waived non-cellular senescence. B Kaplan–Meier curves compare overall survival for the four combined CS and PSi score subgroups in GSE39582. The grouping of CRC samples is shown at the bottom of the chart. p < 0.05 in the two-sided log-rank test was considered statistically significant. C A heatmap visualizing the GSVA enrichment analysis shows the activation states of biological pathways under four subgroups of CS and Psi Score. Red, activated pathways; blue, inhibited pathways

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