Fig. 1
From: Harnessing ferroptosis for precision oncology: challenges and prospects
Overview of publication trends from 2012 to 2022 related to specific established cell death mechanisms. a Total number of publications. b Publications focused exclusively on cancer research. In both cases, the data on ferroptosis were fitted to an exponential growth curve (curve in red: y = y0ekt, where t is the time, y is the number of publication at time t, y0 is the initial quantity in the first year considered, e is the base of the natural logarithm, and k is the growth rate constant). R2 is the coefficient of determination and Td, or doubling time, is a metric that quantifies the time (expressed here in years) it takes for the number of published articles on ferroptosis to double. A search for publications on these cell death subroutines was conducted in October 2024 using the Science Citation Index Expanded (SCI-EXPANDED) database of the Web of Science Core Collection (WoSCC). The retrieval formulas, adapted and expanded from Wu et al. (2023) [37], are provided in SI part 1—Advanced search formulas