Table 3 Differentially expressed proteins in NCM713 and MutCM713 (P < 0.05, fold change < 0.67 or > 1.5)
Gene symbol | Description | Log2 (MutCM713/NCM713) | -Log p-value (MutCM713/NCM713) |
|---|---|---|---|
GM2A | Ganglioside GM2 activator |  − 0.694149 | 1.91819 |
SFXN1 | Sideroflexin-1 |  − 0.81672 | 1.77768 |
CPT2 | Carnitine O-palmitoyltransferase 2, mitochondrial |  − 0.698841 | 1.52771 |
PDHX | Pyruvate dehydrogenase protein X component, mitochondrial |  − 0.603498 | 1.49836 |
UQCRC1 | Cytochrome b-c1 complex subunit 1, mitochondrial |  − 0.765833 | 1.36663 |
STK10 | Serine/threonine-protein kinase 10 |  − 0.834714 | 1.33943 |
COMMD5 | COMM domain-containing protein 5 |  − 0.82656 | 1.33601 |
SCO2 | Protein SCO2 homolog, mitochondrial |  − 0.814162 | 1.32631 |
RILPL1 | RILP-like protein 1 | 0.937744 | 1.81486 |
PAK4 | Serine/threonine-protein kinase PAK 4 | 0.641412 | 1.68363 |
UBE2T | Ubiquitin-conjugating enzyme E2 T | 0.588593 | 1.66681 |
IGBP1 | Immunoglobulin-binding protein 1 | 0.732626 | 1.6226 |
CASP3 | Caspase-3 | 0.84637 | 1.60562 |
MKI67 | Proliferation marker protein Ki-67 | 0.800139 | 1.58454 |
PAPSS2 | Bifunctional 3′-phosphoadenosine 5′-phosphosulfate synthase 2 | 1.55965 | 1.55244 |
CNN3 | Calponin-3 | 0.835441 | 1.53682 |
PFAS | Phosphoribosylformylglycinamidine synthase | 0.835115 | 1.53488 |
MICAL3 | [F-actin]-monooxygenase MICAL3 | 0.612276 | 1.49758 |
NCAPD2 | Condensin complex subunit 1 | 0.932126 | 1.49304 |
PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | 0.997645 | 1.48928 |
ELP3 | Elongator complex protein 3 | 0.767206 | 1.48157 |
CAVIN1 | Caveolae-associated protein 1 | 0.818513 | 1.47211 |
IK | Protein red | 0.588484 | 1.46609 |
ALDH1A1 | Retinal dehydrogenase 1 | 1.2972 | 1.44753 |
UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.669125 | 1.44209 |
PARVA | Alpha-parvin | 0.70772 | 1.42809 |
DDX21 | Nucleolar RNA helicase 2 | 0.64949 | 1.41739 |
UBE2E3 | Ubiquitin-conjugating enzyme E2 E3 | 0.767135 | 1.35759 |
PLEKHA5 | Pleckstrin homology domain-containing family A member 5 | 0.648232 | 1.35444 |
DPY30 | Protein dpy-30 homolog | 0.842432 | 1.34108 |
H2AZ2 | Histone H2A.V | 0.832712 | 1.33525 |
STAT6 | Signal transducer and activator of transcription 6 | 0.979335 | 1.32424 |
INTS9 | Integrator complex subunit 9 | 0.712528 | 1.30905 |
HEATR1 | HEAT repeat-containing protein 1 | 0.596261 | 1.30523 |
U2SURP | U2 snRNP-associated SURP motif-containing protein | 0.813351 | 1.30466 |
PAFAH1B2 | Platelet-activating factor acetylhydrolase IB subunit alpha2 | 0.724424 | 1.30301 |