Fig. 7
Transcriptomic comparisons of NCM713, MutCM713, and 92.1. a Heatmap of relative expression of melanocyte markers shown in z-score. Volcano plot of b NCM713 vs. 92.1 and c NCM713 vs. MutCM713. Significantly upregulated and downregulated genes appear in blue and red, respectively (P < 0.05, Log2(fold change) < − 1 or > 1). d Venn diagram of differential gene expression analysis of NCM713 vs. 92.1 and NCM713 vs. MutCM713 (P < 0.05, Log2(fold change) < − 1 or > 1). e Selected regulated pathways identified by KEGG Pathway Enrichment Analysis of commonly regulated genes in 92.1 and MutCM713. A full list can be found in Additional file 6. f Heatmap of selected gene expression of interest