Table 1 Significant SFFLs comprising genes with differential expression in the pseudotime trajectory between neoplastic and OPC clusters and concurrent differential APA events
From: Unveiling cell-type-specific microRNA networks through alternative polyadenylation in glioblastoma
Cluster | MicroRNA family | Transcription factor | Target gene |
|---|---|---|---|
Neoplastic | MIR153-1/MIR153-2 | SP3 | IRS2 |
Neoplastic | MIR155 | JUN | LOX |
Neoplastic | MIR155 | STAT1 | IL6ST |
Neoplastic | MIR32 | SP3 | IRS2 |
OPC | MIR101-1/MIR101-2 | CREB1 | PEB1 |
OPC | MIR143 | AR | PEB1 |
OPC | MIR214 | TP53 | PEB1 |
OPC | MIR27A | AR | PEB1 |
OPC | MIR27A | TP53 | PEB1 |
OPC | MIR194-2 | TP53 | PEB1 |
OPC | MIR214 | JUN | ITGB8 |
OPC | MIR214 | JUN | PTX3 |