Fig. 4

Twenty-four-hour insecticide contact bioassays with transgenic flies over-expressing CYP6P4a alleles exposed to (A) permethrin, B deltamethrin, and (C) alphacypermethrin and transgenic flies over-expressing CYP6P4b alleles exposed to (D) permethrin, E deltamethrin, and (F) alphacypermethrin. Data shown is mean ± S.E.M; significant difference in mortality is indicated for the GHA vs control and FANG vs control comparisons. Cumulative mortalities of transgenic flies and control flies to insecticides for all six time points. G For CYP6P4a transgenic fly experiment. H For CYP6P4b transgenic fly experiment. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001