Table 1 Selected developmentally regulated SIDER2-containing transcripts encoding known Leishmania virulence factors

LINF_220012800

A2 protein

+

+

-

LINF_220012600, LINF_220012400,

A2-related

+

+

-

LINF_220014400

LINF_220014500, LINF_220012300

3'a2rel-related protein

+

-

-

LINF_300020200

p1/s1 nuclease (3'-nucleotidase/nuclease)

+

+

-

LINF_330037600

cysteine peptidase - Clan CA - family C51 putative

+

+

-

LINF_160019700

OTU-like cysteine protease - putative

-

+

-

LINF_130006900

Lipase (class 3) - putative

+

+

-

LINF_230007900

argininosuccinate synthase – putative

+

+

-

LINF_360058200

Sugar efflux transporter (SWEET)

+

+

-

LINF_110012300

Protein Associated with Differentiation

+

+

-

LINF_340039100

aminophospholipid translocase – putative

+

+

-

LINF_140008800

Plasma-membrane choline transporter - putative

+

+

-

LINF_300028900

sphingosine 1-phosphate lyase

-

+

(+)

LINF_070013000

malonyl-coa decarboxylase-like protein

+

+

-

LINF_240017900, LINF_280019700

amastin-like surface protein-like protein

+

-

-

LINF_260013000

glutathione peroxidase-like / tryparedoxin peroxidase

+

-

-

LINF_020006900

phosphoglycan beta 1-3 galactosyltransferase

+

-

-

LINF_050017500

surface antigen-like protein

-

-

+

LINF_120013500

surface antigen protein 2 (PSA-2) - putative

-

-

+

LINF_340037800

lipophosphoglycan biosynthetic protein (lpg2)

-

-

+

LINF_240008400, LINF_240008300

UDP-galactose transporter - putative (LPG5A)

-

-

+

LINF_170015800

META domain containing protein (META2)

-

-

+

LINF_100013850, LINF_100013900

amino acid permease 24 - putative

-

-

+

LINF_340005600

ascorbate peroxidase

-

-

+

LINF_170007400

receptor-type adenylate cyclase

-

-

+

LINF_270016000, LINF_270016100

ATP-binding cassette subfamily A - member 1

-

-

+