Table 3 Ablation results of the proposed method on the DrugBank dataset
Setting | AUC | AUPR | Precision | Recall | ACC |
|---|---|---|---|---|---|
w/o incomplete samples | \(0.882_{(\pm 0.003)}\) | \(0.897_{(\pm 0.003)}\) | \(0.805_{(\pm 0.013)}\) | \(0.797_{(\pm 0.002)}\) | \(0.802_{(\pm 0.008)}\) |
w/o conceptual knowledge | \(0.919_{(\pm 0.004)}\) | \(0.920_{(\pm 0.004)}\) | \(0.821_{(\pm 0.004)}\) | \(0.867_{(\pm 0.009)}\) | \(0.839_{(\pm 0.004)}\) |
w/o compound knowledge | \(0.940_{(\pm 0.003)}\) | \(0.940_{(\pm 0.002)}\) | \(0.854_{(\pm 0.014)}\) | \(0.875_{(\pm 0.012)}\) | \(0.863_{(\pm 0.008)}\) |
w/o protein knowledge | \(0.949_{(\pm 0.002)}\) | \(0.947_{(\pm 0.002)}\) | \(0.860_{(\pm 0.011)}\) | \(0.892_{(\pm 0.008)}\) | \(0.873_{(\pm 0.004)}\) |
Full dataset | \({\textbf {0.962}}_{(\pm 0.001)}\) | \({\textbf {0.961}}_{(\pm 0.002)}\) | \({\textbf {0.875}}_{(\pm 0.008)}\) | \({\textbf {0.922}}_{(\pm 0.006)}\) | \({\textbf {0.895}}_{(\pm 0.004)}\) |