Fig. 3

Estimating RNA Velocity of M2 by using scVelo. a Velocities derived from the dynamical model for M2 are visualized as streamlines in a UMAP-based embedding. b Gene expression dynamics resolved along latent time showed a clear cascade of transcription in the top 300 likelihood-ranked genes. c Top five cluster-specific driver genes of cluster 0 displayed pronounced dynamic behavior. d Top five cluster-specific driver genes of cluster 2 displayed pronounced dynamic behavior. e Top five cluster-specific driver genes of cluster 16 displayed pronounced dynamic behavior