Fig. 5

The DNA methylation dynamics during myogenic differentiation. A Gene elements profiling analysis by CpG-type methylation was visualized in a line plot. The element segments including genebody, upstream 2 kb (promoter) and downstream 2 kb, were divided into 20 bin, and the methylation level in each bin reflected the general trend of methylation level change of gene segment. The average methylation level for all genes in each bin was reflected in to the line plot. The light blue line represents GM, while the pink line represents DM. B CG-type DMRs located at promoter region (DMPs) were visualized in a volcano plot. FC ≥ 10% and P < 0.05 were considered as the threshold for DMPs. The blue plots represent the DMPs P < 0.05 and FC ≤  − 10%, red plots represent the DMPs P < 0.05 and FC ≥ 10%. C The top 10 Biological Process GO terms enriched by CG-type DMPs. The vertical axis is the GO term name and the horizontal axis is -log₁₀P-value