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Fig. 5 | BMC Biology

Fig. 5

From: Hypoxia and Foxn1 alter the proteomic signature of dermal fibroblasts to redirect scarless wound healing to scar-forming skin wound healing in Foxn1−/− mice

Fig. 5

Oxygen availability (normoxia vs. hypoxia) modulates DFs: proliferation (A), metabolic activity (B) and migration (C). Foxn1.−/− DFs cultured under hypoxic or normoxic conditions with KCM (keratinocyte conditioned media) from Ad-Foxn1- or Ad-GFP-transduced keratinocytes were analysed with a BrdU incorporation assay followed by flow cytometry analysis (A; n = 4), MTT metabolic activity assay (B; n = 4) or scratch migratory assay (C; n = 4). Values are the lsmean ± SE; asterisks indicate significant differences between normoxic or hypoxic condition transduction (**p < 0.01)

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