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Fig. 2 | BMC Biology

Fig. 2

From: Hypoxia and Foxn1 alter the proteomic signature of dermal fibroblasts to redirect scarless wound healing to scar-forming skin wound healing in Foxn1−/− mice

Fig. 2

Classification of DF proteins regulated upon hypoxia (1% O2) vs. normoxia (21% O2) that were cocultured with Ad-Foxn1 (A)- or Ad-GFP (B)-transduced keratinocytes for 24 h according to GO using PANTHER and enriched with the g: Profiler database. A, B Diagrams illustrate detected proteins in terms of “molecular function” (with detailed proteins included in the catalytic activity class). C, D Heatmap of DF proteins linked to ECM organization (C) or the proteins interacting with ECM (D) enriched by hypoxia separately for coculture with Ad-Foxn1 or Ad-GFP keratinocytes. The scale bar in the heatmap indicates protein fold changes ranging from + 12 to − 1

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BMC Biology

ISSN: 1741-7007

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