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Fig. 10 | BMC Biology

Fig. 10

From: Hypoxia and Foxn1 alter the proteomic signature of dermal fibroblasts to redirect scarless wound healing to scar-forming skin wound healing in Foxn1−/− mice

Fig. 10

Evaluation of collagen type I vs. collagen type III content in stained picrosirius red histological skin sections collected from LV-eGFP (control)-, LV-Hif-1α- or LV-Hif-1α + LV-Foxn1-treated Foxn1−/− mice at day 6 (A–D) and day 14 (E–G and I) after injury. Representative histological sections of wounded (A–C; E–G; n = 3 per LV treatment) and unwounded skin (H; n = 3) were analysed. Collagen fibres: yellow‒red (collagen type I) and green (collagen type III) were evaluated as a Relative Object Count [%] at postwounding days 6 (D) and 14 (I). Scale bar (A-G) 200 µm, insets (A–G) 50 µm and (H) 50 µm; wb – wound bed

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