Fig. 3
From: The m6A writer KIAA1429 regulates photoaging progression via MFAP4-dependent collagen synthesis
DMMGs were involved in collagen metabolism in UV-induced photoaging. A Hierarchical cluster analysis of DMMGs between the control group and photoaged group. B MeRIP-qPCR analysis validated the m6A levels of the top 5 hyper-methylation and 5 hypo-methylation genes (n = 7). m6A-IP/input and IgG-IP/input were used to calculate the enrichment of m6A in each group. C Volcano plot of DEGs between the two groups. D RT-qPCR validated the top DEGs between the two groups (n = 7). E Venn diagram of genes with a significant change in both the m6A methylation and mRNA expression levels. F The top 20 GO biological processes enrichments of genes from the hyper-down part. All data were presented as mean ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001