Fig. 4

Post-developmental HRJD expression in ISC lineages extends organismal lifespan. A–D Survival curve for organismal lifespan by sex. HRJDs are induced by esgts-Gal4 (A and B) and Act5C-Gal4 (C and D). For temporal regulation of HRJD induction using tub-Gal80ts (A and B), adult flies were transferred to 29 °C at day 3. N.S., not significant: P > 0.05, *P < 0.05, **P ≤ 0.01, ***P ≤ 0.001, Log-rank tests. n indicates the number of flies. See also Additional file 1: Fig. S3