Fig. 1

A Representative CD68 immunohistochemistry (brown) showing multinucleated adipoclasts (red arrows) in the white adipose tissue of obese patients undergoing bariatric surgery; scale bar, 50μm. B Macrophage fusion and multinucleation in health and disease. In addition to osteoclasts, foreign body giant cells and MGCs, adipoclasts contribute to the clearance of stressed adipocytes in the white adipose tissue