Fig. 1.
From: From top to bottom: Cell polarity in Hedgehog and Wnt trafficking
Apical ligand recycling in source cell. Endocytosis-regulated Wnt/Wg and Hh secretion. After formation and lipid modification of the ligand, chaperones transport the ligands to the apical side of the source cell. The ligands get re-endocytosed and packaged on exosomes for subsequent secretion at the basolateral side