Figure 3
From: Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site
Predicted active site of human glutaminyl cyclase. Figure 5 represents the five conserved human QC residues corresponding to the zinc ligands of the bacterial aminopeptidase plus the conserved glutamate corresponding to the general base of the aminopeptidase. QC numbering from the top (clockwise): His 330, Glu 202, Glu 201, His 140, Asp 248, Asp 159. See Table 1 for comparisons with 1AMP.